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Expression of Leukotriene B(4) receptor-1 on CD8(+) T cells is required for their migration into tumors to elicit effective antitumor immunity

Leukotriene B(4) (LTB(4)) receptor, BLT1 is expressed on variety of immune cells and has been implicated as a mediator of diverse inflammatory diseases. However, whether biological responses initiated via this receptor generate tumor promoting inflammation or anti-tumor immunity remains unexplored....

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Detalhes bibliográficos
Main Authors: Sharma, Rajesh Kumar, Chheda, Zinal, Jala, Venkatakrishna Rao, Haribabu, Bodduluri
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815560/
https://ncbi.nlm.nih.gov/pubmed/23960231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300967
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