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NADPH Oxidase-Derived Superoxide Provides a Third Signal for CD4 T cell Effector Responses

Originally recognized for their direct induced toxicity as a component of the innate immune response, reactive oxygen species (ROS) can profoundly modulate T cell adaptive immune responses. Efficient T cell activation requires: signal 1, consisting of an antigenic peptide-MHC complex binding with th...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Padgett, Lindsey E., Tse, Hubert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992601/
https://ncbi.nlm.nih.gov/pubmed/27474077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502581
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