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Divergent synthesis and identification of the cellular targets of deoxyelephantopins
Herbal extracts containing sesquiterpene lactones have been extensively used in traditional medicine and are known to be rich in α,β-unsaturated functionalities that can covalently engage target proteins. Here we report synthetic methodologies to access analogues of deoxyelephantopin, a sesquiterpen...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992173/ https://ncbi.nlm.nih.gov/pubmed/27539788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12470 |
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