Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

Advanced colorectal cancer is one of the deadliest cancers, with a 5-year survival rate of only 12% for patients with the metastatic disease. Checkpoint inhibitors, such as the antibodies inhibiting the PD-1/PD-L1 axis, are among the most promising immunotherapies for patients with advanced colon ca...

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Veröffentlicht in:Nat Commun
Hauptverfasser: He, Chunbai, Duan, Xiaopin, Guo, Nining, Chan, Christina, Poon, Christopher, Weichselbaum, Ralph R., Lin, Wenbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992065/
https://ncbi.nlm.nih.gov/pubmed/27530650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12499
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