Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

The transcription factor hepatocyte nuclear factor 1β (HNF1β) is ubiquitously overexpressed in ovarian clear cell carcinoma (CCC) and is a potential therapeutic target. To explore potential approaches that block HNF1β transcription we have identified and characterised extensively the nuclear localis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Struct Biol
Egile Nagusiak: Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Academic Press 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991853/
https://ncbi.nlm.nih.gov/pubmed/27346421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.06.018
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak