The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). Here, we have used primary human monocyte-derived macrophages differentiate...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Badia, Roger, Pujantell, Maria, Riveira-Muñoz, Eva, Puig, Teresa, Torres-Torronteras, Javier, Martí, Ramón, Clotet, Bonaventura, Ampudia, Rosa M., Vives-Pi, Marta, Esté, José A., Ballana, Ester
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991798/
https://ncbi.nlm.nih.gov/pubmed/27541004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005829
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