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Substrate Modulus Regulates Osteogenic Differentiation of Rat Mesenchymal Stem Cells through Integrin β1 and BMP Receptor Type IA

Osteoblast differentiation of mesenchymal stem cells is regulated by both soluble factor (e.g., bone morphogenetic proteins (BMP)) and mechanically transduced signaling, but the mechanisms have only been partially elucidated. In this study, physical association of BMP Receptor I (BMPRI) with integri...

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Dettagli Bibliografici
Pubblicato in:J Mater Chem B Mater Biol Med
Autori principali: Guo, R., Lu, S., Merkel, A. R., Sterling, J.A., Guelcher, S.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991780/
https://ncbi.nlm.nih.gov/pubmed/27551426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5TB02747K
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