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Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma

Thrombospondin-1 (THBS-1) has been demonstrated to have a complicated role in human cancer and to exert stimulatory and inhibitory effects in different types of tumors. DNA methylation, as the most frequent mechanism for gene silencing, has been widely investigated in regards to the development of t...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Huang, Chuang, Zhou, Xiaohong, Li, Zhenhua, Liu, Hong, He, Yun, Ye, Guo, Huang, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991671/
https://ncbi.nlm.nih.gov/pubmed/27485791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5580
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