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Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma

Thrombospondin-1 (THBS-1) has been demonstrated to have a complicated role in human cancer and to exert stimulatory and inhibitory effects in different types of tumors. DNA methylation, as the most frequent mechanism for gene silencing, has been widely investigated in regards to the development of t...

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Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: Huang, Chuang, Zhou, Xiaohong, Li, Zhenhua, Liu, Hong, He, Yun, Ye, Guo, Huang, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991671/
https://ncbi.nlm.nih.gov/pubmed/27485791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5580
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