ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

Drug-induced aberrant DNA methylation is the first identified epigenetic marker involved in chemotherapy resistance. Understanding how the aberrant DNA methylation is acquired would impact cancer treatment in theory and practice. In this study we systematically investigated whether and how ERα prope...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Si, Xinxin, Liu, Yue, Lv, Jinghuan, Ding, Haijian, Zhang, Xin A., Shao, Lipei, Yang, Nan, Cheng, He, Sun, Luan, Zhu, Dongliang, Yang, Yin, Li, Andi, Han, Xiao, Sun, Yujie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991505/
https://ncbi.nlm.nih.gov/pubmed/26980709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8038
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