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Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules.

Any effect of serum on the antigenicity of peptides is potentially relevant to their use as immunogens in vivo. Here we demonstrate that serum contains distinct proteases that can increase or decrease the antigenicity of peptides. By using a functional assay, we show that a serum component other tha...

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Détails bibliographiques
Auteurs principaux: Falo, L D, Colarusso, L J, Benacerraf, B, Rock, K L
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC49915/
https://ncbi.nlm.nih.gov/pubmed/1518868
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