Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules.
Any effect of serum on the antigenicity of peptides is potentially relevant to their use as immunogens in vivo. Here we demonstrate that serum contains distinct proteases that can increase or decrease the antigenicity of peptides. By using a functional assay, we show that a serum component other tha...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1992
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1518868/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8347 |
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