Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

The tumor microenvironment is emerging as a key regulator of cancer growth and progression, however the exact mechanisms of interaction with the tumor are poorly understood. Whilst the majority of genomic profiling efforts thus far have focused on the tumor, here we investigate RNA-Seq as a hypothes...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Bradford, James R., Wappett, Mark, Beran, Garry, Logie, Armelle, Delpuech, Oona, Brown, Henry, Boros, Joanna, Camp, Nicola J., McEwen, Robert, Mazzola, Anne Marie, D'Cruz, Celina, Barry, Simon T.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991491/
https://ncbi.nlm.nih.gov/pubmed/26980748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8014
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