Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

The tumor microenvironment is emerging as a key regulator of cancer growth and progression, however the exact mechanisms of interaction with the tumor are poorly understood. Whilst the majority of genomic profiling efforts thus far have focused on the tumor, here we investigate RNA-Seq as a hypothes...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bradford, James R., Wappett, Mark, Beran, Garry, Logie, Armelle, Delpuech, Oona, Brown, Henry, Boros, Joanna, Camp, Nicola J., McEwen, Robert, Mazzola, Anne Marie, D'Cruz, Celina, Barry, Simon T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991491/
https://ncbi.nlm.nih.gov/pubmed/26980748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8014
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