Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis

Neutrophils play a central role in innate immunity and are rapidly recruited to sites of infection and injury. Neutrophil apoptosis is essential for the successful resolution of inflammation. Necrostatin-1 (Nec-1,methyl-thiohydantoin-tryptophan (MTH-Trp)), is a potent and specific inhibitor of necro...

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Publicado en:Oncotarget
Autores principales: Jie, Hongyu, He, Yi, Huang, Xuechan, Zhou, Qingyou, Han, Yanping, Li, Xing, Bai, Yongkun, Sun, Erwei
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Autophagy and Cell Death
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991389/
https://ncbi.nlm.nih.gov/pubmed/27027357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8346
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