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Improved dissolution and anti-inflammatory activity of ibuprofen-polyethylene glycol 8000 solid dispersion systems

BACKGROUND: The purpose of this study was to develop ibuprofen (IB)-polyethylene glycol (PEG) 8000 solid dispersions (SDs) and investigate them for in vitro dissolution and in vivo anti-inflammatory activity. MATERIALS AND METHODS: IB-PEG 8000 SDs were prepared by fusion method using varying combina...

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Bibliografische gegevens
Gepubliceerd in:Int J Pharm Investig
Hoofdauteurs: Ofokansi, Kenneth C., Kenechukwu, Franklin C., Ezugwu, Richard O., Attama, Anthony A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Medknow Publications & Media Pvt Ltd 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991122/
https://ncbi.nlm.nih.gov/pubmed/27606257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.187344
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