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Development of prednisone: Polyethylene glycol 6000 fast-release tablets from solid dispersions: Solid-state characterization, dissolution behavior, and formulation parameters

The aim of the current study was to design oral fast-release polymeric tablets of prednisone and to optimize the drug dissolution profile by modifying the carrier concentration. Solid dispersions were prepared by the solvent evaporation method at different drug:polymer ratios (wt/wt). The physical s...

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Detalhes bibliográficos
Main Authors: Leonardi, Darío, Barrera, María Gabriela, Lamas, María Celina, Salomón, Claudio Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750694/
https://ncbi.nlm.nih.gov/pubmed/18181529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0804108
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