Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice

BACKGROUND: VE-cadherin is the chief constituent of endothelial adherens junctions. However, the role of VE-cadherin in the pathogenesis of cerebrovascular diseases including brain ischemia has not yet been investigated. METHODS: VE-cadherin heterozygous (VEC(+/-)) mice and wildtype controls were su...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Gertz, Karen, Kronenberg, Golo, Uhlemann, Ria, Prinz, Vincent, Marquina, Ruben, Corada, Monica, Dejana, Elisabetta, Endres, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991103/
https://ncbi.nlm.nih.gov/pubmed/27538712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-016-0670-8
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