The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

BACKGROUND: After viral infection and the stimulation of some pattern-recognition receptors, TANK-binding kinase I (TBK1) is activated by K63-linked polyubiquitination followed by trans-autophosphorylation. While the activated TBK1 induces type I interferon production by phosphorylating the transcri...

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Bibliografiska uppgifter
I publikationen:BMC Biol
Huvudupphovsmän: Pourcelot, Marie, Zemirli, Naima, Silva Da Costa, Leandro, Loyant, Roxane, Garcin, Dominique, Vitour, Damien, Munitic, Ivana, Vazquez, Aimé, Arnoult, Damien
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991008/
https://ncbi.nlm.nih.gov/pubmed/27538435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0292-z
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