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The antinociception of oxytocin on colonic hypersensitivity in rats was mediated by inhibition of mast cell degranulation via Ca(2+)-NOS pathway

This study was conducted to investigate the effects of oxytocin (OT) on visceral hypersensitivity/pain and mast cell degranulation and the underlying mechanisms. We found that oxytocin receptor (OTR) was expressed in colonic mast cells in humans and rats, as well as in human mast cell line-1 (HMC-1)...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Rep
المؤلفون الرئيسيون: Gong, Liping, Li, Jing, Tang, Yan, Han, Ting, Wei, Chuanfei, Yu, Xiao, Li, Jingxin, Wang, Rong, Ma, Xuelian, Liu, Kejing, Geng, Lingyun, Liu, Shaozhuang, Yan, Bing, Liu, Chuanyong
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2016
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990927/
https://ncbi.nlm.nih.gov/pubmed/27538454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31452
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