Pannexin-1 Channels Are Essential for Mast Cell Degranulation Triggered During Type I Hypersensitivity Reactions

Mast cells (MCs) release pro-inflammatory mediators through a process called degranulation response. The latter may be induced by several conditions, including antigen recognition through immunoglobulin E (IgE) or “cross-linking,” classically associated with Type I hypersensitivity reactions. Early...

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Udgivet i:Front Immunol
Main Authors: Harcha, Paloma A., López, Ximena, Sáez, Pablo J., Fernández, Paola, Barría, Iván, Martínez, Agustín D., Sáez, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896164/
https://ncbi.nlm.nih.gov/pubmed/31849935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02703
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