SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells

Shugoshin 1 (SGO1) is required for accurate chromosome segregation during mitosis and meiosis; however, its other functions, especially at interphase, are not clearly understood. Here, we found that downregulation of SGO1 caused a synergistic phenotype in cells overexpressing MYCN. Downregulation of...

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Publicat a:Sci Rep
Autors principals: Murakami-Tonami, Yuko, Ikeda, Haruna, Yamagishi, Ryota, Inayoshi, Mao, Inagaki, Shiho, Kishida, Satoshi, Komata, Yosuke, Jan Koster, J K, Takeuchi, Ichiro, Kondo, Yutaka, Maeda, Tohru, Sekido, Yoshitaka, Murakami, Hiroshi, Kadomatsu, Kenji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990925/
https://ncbi.nlm.nih.gov/pubmed/27539729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31615
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