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Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells

The condensin complex is required for chromosome condensation during mitosis; however, the role of this complex during interphase is unclear. Neuroblastoma is the most common extracranial solid tumor of childhood, and it is often lethal. In human neuroblastoma, MYCN gene amplification is correlated...

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Detalhes bibliográficos
Main Authors: Murakami-Tonami, Yuko, Kishida, Satoshi, Takeuchi, Ichiro, Katou, Yuki, Maris, John M, Ichikawa, Hitoshi, Kondo, Yutaka, Sekido, Yoshitaka, Shirahige, Katsuhiko, Murakami, Hiroshi, Kadomatsu, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013162/
https://ncbi.nlm.nih.gov/pubmed/24553121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27983
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