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TOP2A is overexpressed in and a therapeutic target for adrenocortical carcinoma

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with no effective therapy for patients with locally advanced and metastatic disease. The current study aimed to evaluate expression and function of TOP2A in human adrenocortical neoplasm, and anticancer activity of agents...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Jain, Meenu, Zhang, Lisa, He, Mei, Zhang, Ya-Qin, Patterson, Erin E., Nilubol, Naris, Shen, Min, Kebebew, Electron
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990817/
https://ncbi.nlm.nih.gov/pubmed/23533247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0403
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