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TOP2A is overexpressed in and a therapeutic target for adrenocortical carcinoma

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with no effective therapy for patients with locally advanced and metastatic disease. The current study aimed to evaluate expression and function of TOP2A in human adrenocortical neoplasm, and anticancer activity of agents...

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Dettagli Bibliografici
Pubblicato in:Endocr Relat Cancer
Autori principali: Jain, Meenu, Zhang, Lisa, He, Mei, Zhang, Ya-Qin, Patterson, Erin E., Nilubol, Naris, Shen, Min, Kebebew, Electron
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990817/
https://ncbi.nlm.nih.gov/pubmed/23533247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0403
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