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EMT Reversal in human cancer cells after IR knockdown in hyperinsulinemic mice

Type 2 Diabetes (T2D) is associated with increased cancer risk and cancer-related mortality. Data herein show that we generated an immunodeficient hyperinsulinemic mouse by crossing the Rag1(−/−) mice, which have no mature B or T lymphocytes, with the MKR mouse model of T2D to generate the Rag1(−/−)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Endocr Relat Cancer
Hauptverfasser: Zelenko, Zara, Gallagher, Emily Jane, Antoniou, Irini Markella, Sachdev, Deepali, Nayak, Anupma, Yee, Douglas, LeRoith, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990486/
https://ncbi.nlm.nih.gov/pubmed/27435064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-16-0142
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