A reactivity-based probe of the intracellular labile ferrous iron pool

Improved methods for studying intracellular reactive iron(II) are of significant interest for studies of iron metabolism and disease relevant changes in iron homeostasis. Here we describe a highly-selective reactivity-based probe in which Fenton-type reaction with intracellular labile iron(II) leads...

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Bibliographic Details
Published in:Nat Chem Biol
Main Authors: Spangler, Benjamin, Morgan, Charles W., Fontaine, Shaun D., Vander Wal, Mark N., Chang, Christopher J., Wells, James A., Renslo, Adam R.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990480/
https://ncbi.nlm.nih.gov/pubmed/27376690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2116
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