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A reactivity-based probe of the intracellular labile ferrous iron pool

Improved methods for studying intracellular reactive iron(II) are of significant interest for studies of iron metabolism and disease relevant changes in iron homeostasis. Here we describe a highly-selective reactivity-based probe in which Fenton-type reaction with intracellular labile iron(II) leads...

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Publicat a:Nat Chem Biol
Autors principals: Spangler, Benjamin, Morgan, Charles W., Fontaine, Shaun D., Vander Wal, Mark N., Chang, Christopher J., Wells, James A., Renslo, Adam R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990480/
https://ncbi.nlm.nih.gov/pubmed/27376690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2116
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