A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor

Cervical cancer is one of the leading causes of cancer death in women worldwide. The causative agents of cervical cancers, high-risk human papillomaviruses (HPVs), cause cancer through the action of two oncoproteins, E6 and E7. The E6 oncoprotein cooperates with an E3 ubiquitin ligase (UBE3A) to tar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Padash Barmchi, Mojgan, Gilbert, Mary, Thomas, Miranda, Banks, Lawrence, Zhang, Bing, Auld, Vanessa J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990329/
https://ncbi.nlm.nih.gov/pubmed/27537218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005789
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