A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor

Cervical cancer is one of the leading causes of cancer death in women worldwide. The causative agents of cervical cancers, high-risk human papillomaviruses (HPVs), cause cancer through the action of two oncoproteins, E6 and E7. The E6 oncoprotein cooperates with an E3 ubiquitin ligase (UBE3A) to tar...

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Foilsithe in:PLoS Pathog
Main Authors: Padash Barmchi, Mojgan, Gilbert, Mary, Thomas, Miranda, Banks, Lawrence, Zhang, Bing, Auld, Vanessa J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990329/
https://ncbi.nlm.nih.gov/pubmed/27537218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005789
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