Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family

Colorectal cancer (CRC) is among the most frequent causes of cancer-related deaths worldwide. Thus, there is a need for the development of new therapeutic approaches for the treatment of CRC. Accumulating evidence has revealed that niclosamide, an anthelminthic drug, exerts antitumor activity in sev...

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Pubblicato in:Int J Mol Med
Autori principali: Suliman, Mohammed A., Zhang, Zhenxing, Na, Heya, Ribeiro, Ailton L.L., Zhang, Yu, Niang, Bachir, Hamid, Abdu Salim, Zhang, Hua, Xu, Lijie, Zuo, Yunfei
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990307/
https://ncbi.nlm.nih.gov/pubmed/27460529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2689
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