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Downregulation of CD40 expression contributes to the accumulation of myeloid-derived suppressor cells in gastric tumors
An elevated number of myeloid-derived suppressor cells (MDSCs) in tumor-bearing hosts has been recognized as a crucial mediator of tumor progression due to the cells potent ability to suppress antitumor immunity. Cluster of differentiation (CD) 40, as a suppressive phenotype expressed in MDSCs, is e...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081434/ https://ncbi.nlm.nih.gov/pubmed/25009656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2174 |
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