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Intercellular Variability in Protein Levels from Stochastic Expression and Noisy Cell Cycle Processes
Inside individual cells, expression of genes is inherently stochastic and manifests as cell-to-cell variability or noise in protein copy numbers. Since proteins half-lives can be comparable to the cell-cycle length, randomness in cell-division times generates additional intercellular variability in...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990281/ https://ncbi.nlm.nih.gov/pubmed/27536771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004972 |
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