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Intercellular Variability in Protein Levels from Stochastic Expression and Noisy Cell Cycle Processes

Inside individual cells, expression of genes is inherently stochastic and manifests as cell-to-cell variability or noise in protein copy numbers. Since proteins half-lives can be comparable to the cell-cycle length, randomness in cell-division times generates additional intercellular variability in...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Soltani, Mohammad, Vargas-Garcia, Cesar A., Antunes, Duarte, Singh, Abhyudai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990281/
https://ncbi.nlm.nih.gov/pubmed/27536771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004972
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