Epigenetic dysregulation in the developing Down syndrome cortex

Using Illumina 450K arrays, 1.85% of all analyzed CpG sites were significantly hypermethylated and 0.31% hypomethylated in fetal Down syndrome (DS) cortex throughout the genome. The methylation changes on chromosome 21 appeared to be balanced between hypo- and hyper-methylation, whereas, consistent...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: El Hajj, Nady, Dittrich, Marcus, Böck, Julia, Kraus, Theo F. J., Nanda, Indrajit, Müller, Tobias, Seidmann, Larissa, Tralau, Tim, Galetzka, Danuta, Schneider, Eberhard, Haaf, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990229/
https://ncbi.nlm.nih.gov/pubmed/27245352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1192736
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