Resveratrol improves health and survival of mice on a high-calorie diet

Resveratrol (3,5,4′-trihydroxystilbene) extends the lifespan of diverse species including Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of...

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Published in:Nature
Main Authors: Baur, Joseph A., Pearson, Kevin J., Price, Nathan L., Jamieson, Hamish A., Lerin, Carles, Kalra, Avash, Prabhu, Vinayakumar V., Allard, Joanne S., Lopez-Lluch, Guillermo, Lewis, Kaitlyn, Pistell, Paul J., Poosala, Suresh, Becker, Kevin G., Boss, Olivier, Gwinn, Dana, Wang, Mingyi, Ramaswamy, Sharan, Fishbein, Kenneth W., Spencer, Richard G., Lakatta, Edward G., Le Couteur, David, Shaw, Reuben J., Navas, Placido, Puigserver, Pere, Ingram, Donald K., de Cabo, Rafael, Sinclair, David A.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990206/
https://ncbi.nlm.nih.gov/pubmed/17086191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05354
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