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Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart

Mitochondrial Complex II is a key mitochondrial enzyme connecting the tricarboxylic acid (TCA) cycle and the electron transport chain. Studies of complex II are clinically important since new roles for this enzyme have recently emerged in cell signalling, cancer biology, immune response and neurodeg...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Stepanova, Anna, Shurubor, Yevgeniya, Valsecchi, Federica, Manfredi, Giovanni, Galkin, Alexander
Format: Artigo
Langue:Inglês
Publié: Elsevier Pub. Co 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990131/
https://ncbi.nlm.nih.gov/pubmed/27287543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2016.06.002
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