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Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells

The genetic integrity of each organism is intimately tied to the correct segregation of its genome during mitosis. Insights into the underlying mechanisms are fundamental for both basic research and the development of novel strategies to treat mitosis-relevant diseases such as cancer. Due to their f...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Al-Obaidi, Naowras, Mitchison, Timothy J., Crews, Craig M., Mayer, Thomas U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990065/
https://ncbi.nlm.nih.gov/pubmed/27121275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00203
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