Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.

Two yeast artificial chromosomes (YACs) spanning a total distance of 1.1 megabase pairs of DNA around the MCC (for mutated in colorectal carcinoma) and APC (for adenomatous polyposis coli) genes at 5q21 have been isolated and characterized. Starting from the MCC gene, a strategy was undertaken to id...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hampton, G M, Ward, J R, Cottrell, S, Howe, K, Thomas, H J, Ballhausen, W G, Jones, T, Sheer, D, Solomon, E, Frischauf, A M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8249
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Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.

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