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Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.

Two yeast artificial chromosomes (YACs) spanning a total distance of 1.1 megabase pairs of DNA around the MCC (for mutated in colorectal carcinoma) and APC (for adenomatous polyposis coli) genes at 5q21 have been isolated and characterized. Starting from the MCC gene, a strategy was undertaken to id...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hampton, G M, Ward, J R, Cottrell, S, Howe, K, Thomas, H J, Ballhausen, W G, Jones, T, Sheer, D, Solomon, E, Frischauf, A M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8249
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