Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region.

Two yeast artificial chromosomes (YACs) spanning a total distance of 1.1 megabase pairs of DNA around the MCC (for mutated in colorectal carcinoma) and APC (for adenomatous polyposis coli) genes at 5q21 have been isolated and characterized. Starting from the MCC gene, a strategy was undertaken to id...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Hampton, G M, Ward, J R, Cottrell, S, Howe, K, Thomas, H J, Ballhausen, W G, Jones, T, Sheer, D, Solomon, E, Frischauf, A M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1325652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8249
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