Induction of HEXIM1 activities by HMBA derivative 4a1: functional consequences and mechanism

We have been studying the role of Hexamethylene bisacetamide (HMBA) Induced Protein 1 (HEXIM1) as a tumor suppressor whose expression is decreased in tamoxifen resistant and metastatic breast cancer. HMBA was considered the most potent and specific inducer for HMBA inducible protein 1 (HEXIM1) prior...

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Vydáno v:Cancer Lett
Hlavní autoři: Ketchart, Wannarasmi, Yeh, I-Ju, Zhou, Haoyan, Thiagarajan, Praveena, Lathia, Justin, Reizes, Ofer, Exner, Agata, Su, Bin, Montano, Monica M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988685/
https://ncbi.nlm.nih.gov/pubmed/27238569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.05.029
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