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Polymyxin B Nephrotoxicity: From Organ to Cell Damage

Polymyxins have a long history of dose-limiting toxicity, but the underlying mechanism of polymyxin B-induced nephrotoxicity is unclear. This study investigated the link between the nephrotoxic effects of polymyxin B on renal metabolic functions and mitochondrial morphology in rats and on the struct...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vattimo, Maria de Fátima Fernandes, Watanabe, Mirian, da Fonseca, Cassiane Dezoti, Neiva, Luciana Barros de Moura, Pessoa, Edson Andrade, Borges, Fernanda Teixeira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988638/
https://ncbi.nlm.nih.gov/pubmed/27532263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161057
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