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Role of Heme Oxygenase-1 in Polymyxin B-Induced Nephrotoxicity in Rats
Polymyxin B (PMB) is a cationic polypeptide antibiotic with activity against multidrug-resistant Gram-negative bacteria. PMB-induced nephrotoxicity consists of direct toxicity to the renal tubules and the release of reactive oxygen species (ROS) with oxidative damage. This study evaluated the nephro...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457368/ https://ncbi.nlm.nih.gov/pubmed/22802257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00925-12 |
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