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Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P(2) levels

Myo-inositol is an important cellular osmolyte in autoregulation of cell volume and fluid balance, particularly for mammalian brain and kidney cells. We find it also regulates excitability. Myo-inositol is the precursor of phosphoinositides, key signaling lipids including phosphatidylinositol 4,5-bi...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Dai, Gucan, Yu, Haijie, Kruse, Martin, Traynor-Kaplan, Alexis, Hille, Bertil
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988571/
https://ncbi.nlm.nih.gov/pubmed/27217553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606348113
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