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Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P(2) levels
Myo-inositol is an important cellular osmolyte in autoregulation of cell volume and fluid balance, particularly for mammalian brain and kidney cells. We find it also regulates excitability. Myo-inositol is the precursor of phosphoinositides, key signaling lipids including phosphatidylinositol 4,5-bi...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988571/ https://ncbi.nlm.nih.gov/pubmed/27217553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606348113 |
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