Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression

The Runt-related transcription factors (RUNX) are master regulators of development and major players in tumorigenesis. Interestingly, unlike most transcription factors, RUNX proteins are detected on the mitotic chromatin and apparatus, suggesting that they are functionally active in mitosis. Here, w...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Chuang, Linda Shyue Huey, Khor, Jian Ming, Lai, Soak Kuan, Garg, Shubham, Krishnan, Vaidehi, Koh, Cheng-Gee, Lee, Sang Hyun, Ito, Yoshiaki
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988568/
https://ncbi.nlm.nih.gov/pubmed/27217562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523157113
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