New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

The ubiD/ubiX or the homologous fdc/pad genes have been implicated in the non-oxidative reversible decarboxylation of aromatic substrates, and play a pivotal role in bacterial ubiquinone biosynthesis1–3 or microbial biodegradation of aromatic compounds4–6 respectively. Despite biochemical studies on...

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Veröffentlicht in:Nature
Hauptverfasser: Payne, Karl A.P., White, Mark D., Fisher, Karl, Khara, Basile, Bailey, Samuel S., Parker, David, Rattray, Nicholas J.W., Trivedi, Drupad K., Goodacre, Royston, Beveridge, Rebecca, Barran, Perdita, Rigby, Stephen E.J., Scrutton, Nigel S., Hay, Sam, Leys, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988494/
https://ncbi.nlm.nih.gov/pubmed/26083754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14560
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