Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis

Multiple sclerosis (MS) frequently starts near the lateral ventricles, which are lined by subventricular zone (SVZ) progenitor cells that can migrate to lesions and contribute to repair. Since MS-induced inflammation may decrease SVZ proliferation and thus limit repair, we studied the role of galect...

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Pubblicato in:Glia
Autori principali: James, Rachel E., Hillis, James, Adorján, István, Gration, Betty, Mundim, Mayara V., Iqbal, Asif J., Majumdar, Moon-Moon, Yates, Richard L., Richards, Maureen M.H., Goings, Gwendolyn E., DeLuca, Gabriele C., Greaves, David R., Miller, Stephen D., Szele, Francis G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988318/
https://ncbi.nlm.nih.gov/pubmed/26337870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22906
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