Cuprizone demyelination induces a unique inflammatory response in the subventricular zone

BACKGROUND: Cuprizone leads to demyelination of the corpus callosum (CC) and activates progenitor cells in the adjacent subventricular zone (SVZ), a stem cell niche which contributes to remyelination. The healthy SVZ contains semi-activated microglia and constitutively expresses the pro-inflammatory...

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Publicado en:J Neuroinflammation
Autores principales: Hillis, James M., Davies, Julie, Mundim, Mayara Vieira, Al-Dalahmah, Osama, Szele, Francis G.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994223/
https://ncbi.nlm.nih.gov/pubmed/27550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0651-2
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