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Primary Mitochondrial Disease and Secondary Mitochondrial Dysfunction: Importance of Distinction for Diagnosis and Treatment

Mitochondrial disease refers to a heterogeneous group of disorders resulting in defective cellular energy production due to abnormal oxidative phosphorylation (oxphos). Primary mitochondrial disease (PMD) is diagnosed clinically and ideally, but not always, confirmed by a known or indisputably patho...

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Detalhes bibliográficos
Publicado no:Mol Syndromol
Main Authors: Niyazov, Dmitriy M., Kahler, Stephan G., Frye, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988248/
https://ncbi.nlm.nih.gov/pubmed/27587988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000446586
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