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ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to retain the structural integrity and function of the macromolecule. The ConSurf web server (http://consurf.tau.ac.il), e...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Ashkenazy, Haim, Abadi, Shiran, Martz, Eric, Chay, Ofer, Mayrose, Itay, Pupko, Tal, Ben-Tal, Nir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987940/
https://ncbi.nlm.nih.gov/pubmed/27166375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw408
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