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ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under strong evolutionary constraints. Thus, the biological importance of a residue often correlates with its...

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Detalhes bibliográficos
Main Authors: Landau, Meytal, Mayrose, Itay, Rosenberg, Yossi, Glaser, Fabian, Martz, Eric, Pupko, Tal, Ben-Tal, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160131/
https://ncbi.nlm.nih.gov/pubmed/15980475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki370
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